Treatment with Kaletra should be prescribed by a doctor who has experience in the management of HIV infection.
In adults and adolescents (aged 12 years and over), the recommended dose of Kaletra is three capsules or two 200/50-mg tablets twice a day. This dose is also suitable for children (aged between two and 12 years) provided that they weigh more than 40 kg and have a body surface area (calculated using the child?s height and weight) over 1.4 m 2. The dose for smaller children depends on the child?s body surface area and the other medicines that the child is taking.
If necessary, adults (aged 18 years or over) can take the full dose of four tablets as a single daily dose if they are infected with HIV that is likely to respond to most medicines in the same class as Kaletra (protease inhibitors). When deciding to use once-daily dosing, the doctor should consider the fact that it might not be as effective as twice-daily dosing at keeping HIV levels low in the long term and may increase the risk of diarrhoea.
The oral solution is for patients who cannot take the tablets or capsules. The capsules and oral solution must be taken with food, but the tablets can be taken with or without food. Kaletra tablets should be swallowed whole and not chewed, broken or crushed. For more information, see the package leaflet.