The side effects seen with Omnitrope were similar in type and severity to those seen with the reference medicine Genotropin. The most common side effects (seen in between 1 and 10 patients in 100) are, in children, transient local skin reactions at the site of injection, and in adults, mild oedema (accumulation of fluid), paraesthesia (numbness or tingling), joint and muscle pain (especially in the hip or knee) and stiffness of the limbs. In addition, as with all protein medicines, some patients may develop antibodies (proteins that are produced in response to Omnitrope). However these have no growth-inhibiting effects. For the full list of all side effects reported with Omnitrope, see the Package Leaflet.
Omnitrope should not be used in people who may be hypersensitive (allergic) to somatropin or any of the other ingredients (the ready-to-use solution and the solvent for Omnitrope 5 mg/ml contain benzyl alcohol). Omnitrope should not be used when the patient suffers from an active tumour or an acute life-threatening illness. For the full list of restrictions, see the Package Leaflet.
Somatropin may interfere with the body?s use of insulin. Blood sugar levels will need to be checked during treatment, and treatment with insulin may sometimes need to be adjusted or started.