The most common side effects with SonoVue (seen in between 1 and 10 patients in 100) are headache, paraesthesia (unusual sensations like pins and needles), dizziness, dysgeusia (taste disturbances), flushing (reddening of the skin), pharyngitis (sore throat), nausea (feeling sick), pruritus (itching), rash, pain, including back and chest pain, chest discomfort, fatigue (tiredness), reactions at the injection site, feeling hot and raised blood sugar levels. For the full list of all side effects reported with SonoVue, see the package leaflet.
SonoVue should not be used in people who may be hypersensitive (allergic) to sulphur hexafluoride or any of the other ingredients. SonoVue must also not be used in the following patients:
patients with recent acute coronary syndrome symptoms involving the heart or unstable ischaemic cardiac disease reduced blood supply to the heart
patients known to have right-to-left shunts abnormal movement of blood within the heart, severe pulmonary hypertension high blood pressure in the pulmonary artery, the blood vessel that leads from the heart to the lungs, uncontrolled hypertension high blood pressure or adult respiratory distress syndrome severe fluid build-up in both lungs
pregnant or breast-feeding women.