The most commonly reported side effects are visual disturbances, fever, rash, nausea, vomiting, diarrhoea, headache, and swelling of the extremities. Stomach pains and changes in stools should be reported to a doctor. For the full list of all side effects reported with VFEND, please see the Package Leaflet.
VFEND should not be used in people who may be hypersensitive (allergic) to voriconazole or any of the other ingredients. VFEND should not be used in patients who are taking any of the following medicines:
- Terfenadine, astemizole (used for allergy)
- Cisapride (used for stomach problems)
- Pimozide (used to treat mental illnesses)
- Quinidine (used for irregular heart beat)
- Rifampicin (used to treat tuberculosis)
- Carbamazepine (used to treat seizures)
- Phenobarbital (used for severe insomnia and seizures)
- Ergot alkaloids (e.g. ergotamine, dihydroergotamine; used for migraine)
- Sirolimus (used in transplant patients)
- Efavirenz (used to treat HIV infection)
- Ritonavir (used to treat HIV infection) in doses of 400 mg or more twice daily Caution is also needed when VFEND is taken at the same time as other medicines, see the Package Leaflet for full details.