Barium oxalate succinate

CAS number328-50-7
PUB number51
Drugbank IDDB08845
Empirical formulaC5H6O5
Molar mass (g·mol−1)146,098
Physical statesolid
Density (g·cm−3)1,5
Melting point (°C)113-118
Boiling point (°C)323
PKS value2,66
Solubility53.1 mg/mL

Basics

Alpha-ketoglutaric acid is an essential building block in the citrate cycle and nitrogen transport. It is a dicarboxylic acid and a derivative of n-pentane. It is usually present in the form of colorless and odorless crystals. From a pharmaceutical point of view, alpha-ketoglutaric acid is not yet used as a drug - except in homeopathic remedies. However, it is already the subject of intensive research and is said to help with metabolic disorders and obesity, among other things. Recent studies have demonstrated a muscle protein-building effect that can help patients rebuild muscle after surgery.

Graphic structural formula of the active ingredient alpha-ketoglutaric acid

Effect

Alpha-ketoglutaric acid is an intermediate in the citrate cycle and is converted into succinyl coenzyme A by a dehydrogenase. As a nitrogen transporter, amino groups of amino acids can be attached to the respective molecule and thus transported to the liver, where they then act in the urea cycle.

Dosage

Always take alpha-ketoglutaric acid exactly as described in the package leaflet or as advised by your doctor.

Adults:

The usual recommended dose is 22 mg 1-3 times a week.

The recommended dose for acute symptoms is 22 mg daily for 3 days .

Alpha-ketoglutaric acid is used intramuscularly (application into the muscle), subcutaneously (application under the skin) or intradermally (application into the skin).

Children & adolescents:

The usual recommended dose is 22 mg 1-3 times a week.

The recommended dose for acute symptoms is 22 mg daily for 3 days .

Alpha-ketoglutaric acid is used intramuscularly (application into the muscle), subcutaneously (application under the skin) or intradermally (application into the skin).

Side effects

The following side effects may occur:

  • Allergic reactions
  • Hypersensitivity reactions

Interactions

There are no known interactions, as no studies have been carried out.

Contraindications

Alpha-ketoglutaric acid must NOT be taken in the following cases:

  • In case of allergy to alpha-ketoglutaric acid

Age restriction

Alpha-ketoglutaric acid can be used from the age of 12.

Pregnancy & breastfeeding

Alpha-ketoglutaric acid can be used during pregnancy and breastfeeding after consultation with your doctor.

Thomas Hofko

Thomas Hofko



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The presented content does not replace the original package insert of the medication, especially regarding the dosage and effects of individual products. We cannot assume liability for the accuracy of the data, as the data has been partially converted automatically. Always consult a doctor for diagnoses and other health-related questions.

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