Cetirizine is a selective histamine antagonist and is used in allergic rhinitis and chronic urticaria. It belongs to the second-generation antihistamines.
Indications and use
Cetirizine is an orally active second-generation histamine H1 antagonist effective in the treatment of various allergic symptoms such as sneezing, cough, nasal congestion, and hives. One of the most common uses of this medication is in the treatment of hay fever (allergic rhinitis). However, cetirizine can also be used for symptomatic treatment of other allergic reactions.
Cetirizine is usually administered in the form of film-coated tablets. However, there are also formulations i.e. drops or oral solutions. Dosages are usually 10 mg film-coated tablets and 10 mg/ml or 1 mg/ml as drops and solution.
It was patented by USB Pharmaceuticals in 1981 and was first approved in 1987. It is on the World Health Organization's list of essential medicines and is available as a generic.