| ATC Code | G04BX17, M01AX25 |
| CAS number | 24967-93-9 |
| PUB number | 24766 |
| Drugbank ID | DB09301 |
| Empirical formula | C13H21NO15S |
| Physical state | solid |
Chondroitin sulfate is a naturally occurring molecule in the body. It belongs to the group of glucosaminoglycans. These are formed in the chondroblasts and are an important component of cartilage tissue. Chondroitin sulfate is used for the long-term treatment of arthritis. After some time, there is relief of pain and increased mobility of the joints.
Chondrotitin is a natural component of cartilage tissue. Its structure provides a certain stability against compression and is essential for the cartilage mass of the joints.
Chondroitinsuflate enters the bloodstream via the gastrointestinal tract and is 90% metabolized into minor metabolites. Oral bioavailability is approximately 20%. It takes up to 6 months for maximum effect to be achieved. Plasma protein binding is very low, at only 0.23%. Chondroitin sulfate is not broken down by the liver. The exact mechanism of how this drug is metabolized has not been elucidated. The plasma half-life is approximately 15 hours. Chondroitin sulfate is excreted through the kidneys.
Chondroitin is an extremely safe drug that is neither carcinogenic nor teratogenic. There are no known significant side effects.
Markus Falkenstätter, BSc
Mag. pharm. Stefanie Lehenauer
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