| ATC Code | D08AH30, D09AA10, G01AC02, P01AA02, S02AA05 |
| CAS number | 130-26-7 |
| PUB number | 2788 |
| Drugbank ID | DB04815 |
| Empirical formula | C9H5ClINO |
| Molar mass (g·mol−1) | 305,50 |
| Physical state | solid |
| Melting point (°C) | 178–179 |
Clioquinol (iodochlorohydroxyquin) is an antifungal, antibiotic and antiprotozoal agent. It is neurotoxic in high doses, which is why its licence for oral treatment has been withdrawn. However, it is still used to treat skin infections caused by bacteria or fungi.
Clioquinol is a broad-spectrum antibacterial with antifungal properties. Clioquinol has a bacteriostatic effect, but the exact mechanism of action is unknown.
Topical absorption is rapid and extensive, especially when the skin is covered with an occlusive dressing or when the drug is applied to extensive or eroded areas of skin.
Markus Falkenstätter, BSc
Mag. pharm. Stefanie Lehenauer
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