Dequalinium is a substance from the group of cationic surfactants. It is used as an antiseptic and disinfectant. It is almost always used in the form of the chloride salt dequalinium chloride. It is either applied superficially to the skin or used in the form of vaginal tablets. It is not used systemically.
Effect
Pharmacodynamics
Cationic surfactants increase the cell permeability of bacteria and fungal cells. This also disrupts the enzymes of the pathogens and inactivates them. The biocidal effect occurs after approx. 30 minutes.
Pharmacokinetics
Dequalinium is absorbed only in extremely small amounts. This amount can be neglected. Pharmacokinetic parameters therefore do not play a role.
Toxicity
Side effects
Skin reactions and reactions of the mucous membranes are possible. (vaginal discharge, itching, redness, burning).
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Markus Falkenstätter, BSc Author
Markus Falkenstätter is a writer on pharmaceutical topics in Medikamio's medical editorial team. He is in the last semester of his pharmacy studies at the University of Vienna and loves scientific work in the field of natural sciences.
Mag. pharm. Stefanie Lehenauer Lector
Stefanie Lehenauer has been a freelance writer for Medikamio since 2020 and studied pharmacy at the University of Vienna. She works as a pharmacist in Vienna and her passion is herbal medicines and their effects.
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