Dequalinium is a substance from the group of cationic surfactants. It is used as an antiseptic and disinfectant. It is almost always used in the form of the chloride salt dequalinium chloride. It is either applied superficially to the skin or used in the form of vaginal tablets. It is not used systemically.



Cationic surfactants increase the cell permeability of bacteria and fungal cells. This also disrupts the enzymes of the pathogens and inactivates them. The biocidal effect occurs after approx. 30 minutes.


Dequalinium is absorbed only in extremely small amounts. This amount can be neglected. Pharmacokinetic parameters therefore do not play a role.


Side effects

Skin reactions and reactions of the mucous membranes are possible. (vaginal discharge, itching, redness, burning).

Toxicological data

LD50: 300mg/kg (oral, mouse)

Chemical & physical properties

ATC Code D08AH01, G01AC05, R02AA02
Formula C30H40N4+2
Molar Mass (g·mol−1) 456.678
Physical State solid
Melting Point (°C) 326
CAS Number 6707-58-0
PUB Number 2993
Drugbank ID DB04209

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All information used for the content comes from verified sources (recognised institutions, experts, studies by renowned universities). We attach great importance to the qualification of the authors and the scientific background of the information. Thus, we ensure that our research is based on scientific findings.
Markus Falkenstätter, BSc

Markus Falkenstätter, BSc

Markus Falkenstätter is a writer on pharmaceutical topics in Medikamio's medical editorial team. He is in the last semester of his pharmacy studies at the University of Vienna and loves scientific work in the field of natural sciences.

Mag. pharm. Stefanie Lehenauer

Mag. pharm. Stefanie Lehenauer

Stefanie Lehenauer has been a freelance writer for Medikamio since 2020 and studied pharmacy at the University of Vienna. She works as a pharmacist in Vienna and her passion is herbal medicines and their effects.

The content of this page is an automated and high-quality translation from DeepL. You can find the original content in German here.


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