Dydrogesterone is a drug from the group of progestins. Dydrogesterone is a synthetic derivative of the natural hormone progesterone, which acts in the same way. Dydrogesterone is approved for the treatment of menstrual disorders and for hormonal replacement therapy.
This medicine requires a prescription and is usually taken in the form of film-coated tablets.
Effect
PharmacodynamicsGestagens
act by binding to progesterone receptors on the cell membrane or inside the cell (intracellular). The intracellular receptors bind to the DNA of the cell after contact with a progestin and thus regulate protein expression. Dydrogesterone binds mainly to receptors in the uterus. This promotes healthy growth and shedding of the uterine lining. Dydrogesterone, unlike other progestins, is not contraceptive.
Pharmacokinetics
Dydrogesterone has an oral bioavailability of 28%. It is broken down in the cells of the liver and has a plasma half-life of approximately 5-7 hours.
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Markus Falkenstätter, BSc Author
Markus Falkenstätter is a writer on pharmaceutical topics in Medikamio's medical editorial team. He is in the last semester of his pharmacy studies at the University of Vienna and loves scientific work in the field of natural sciences.
Mag. pharm. Stefanie Lehenauer Lector
Stefanie Lehenauer has been a freelance writer for Medikamio since 2020 and studied pharmacy at the University of Vienna. She works as a pharmacist in Vienna and her passion is herbal medicines and their effects.
The content of this page is an automated and high-quality translation from DeepL. You can find the original content in German here.
