| ATC Code | G02CA03, R03AC04, R03CC04 |
| CAS number | 13392-18-2 |
| PUB number | 3343 |
| Drugbank ID | DB01288 |
| Empirical formula | C17H21NO4 |
| Molar mass (g·mol−1) | 303,35 |
| Physical state | solid |
| Melting point (°C) | 222–223 |
Fenoterol is a drug from the class of β2-sympathomimetics. It belongs to the group of bronchodilators and is used, for example, in bronchial asthma or COPD to facilitate breathing. Fenoterol is always administered in the form of a spray or aerosol. There are also intravenous applications to inhibit contractions. Medicines containing fenoterol require a prescription and are available as mono- or combination preparations.
The mechanism of action of fenoterol is based on binding to β2-adrenoreceptors in the lung. This activates the enzyme adenylate cyclase, and subsequently increases the level of the neurotransmitter cAMP. An increased concentration of cAMP causes a relaxation of the bronchial musculature and thus a widening of the bronchial tubes. This makes breathing considerably easier.
PharmacokineticsFenoterol is broken down in the liver cells and subsequently excreted by the kidneys.
Signs of overdose include chest pain, dizziness, dry mouth, headache, high or low blood pressure, flu-like symptoms, high blood sugar, muscle cramps, nausea, tremors, and seizures.
Markus Falkenstätter, BSc
Mag. pharm. Stefanie Lehenauer
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