Flupentixol is a highly potent member of the neuroleptic drug class. It is used for the treatment of schizophrenia. It is used especially in patients with poor compliance and many relapses. For this reason, it is often administered as an injection given several times a week.
Flupentixol is available only on prescription.
Effect
Pharmacodynamics
Flupentixol is an antianxiety and mood elevating neuroleptic. It is a high-affinity antagonist at the dopamine receptors D1 and D2. This increases the neurotransmitters serotonin and norepinephrine, which exert a positive effect on mood and thinking.
Pharmacokinetics
Absorption after oral administration is rather slow and poor. Flupentixol is more than 95% bound to plasma proteins. It is primarily cleared by the liver and subsequently excreted in the urine. The elimination half-life is 19-39 hours.
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Markus Falkenstätter, BSc Author
Markus Falkenstätter is a writer on pharmaceutical topics in Medikamio's medical editorial team. He is in the last semester of his pharmacy studies at the University of Vienna and loves scientific work in the field of natural sciences.
Mag. pharm. Stefanie Lehenauer Lector
Stefanie Lehenauer has been a freelance writer for Medikamio since 2020 and studied pharmacy at the University of Vienna. She works as a pharmacist in Vienna and her passion is herbal medicines and their effects.
The content of this page is an automated and high-quality translation from DeepL. You can find the original content in German here.
