Magnesium oxide

Magnesium oxide
ATC Code A02AA02, A06AD02, A12CC10
Formula MgO
Molar Mass (g·mol−1) 40,304
Physical State solid
Density (g·cm−3) 3,58
Melting Point (°C) 2800
Boiling Point (°C) 3600
CAS Number 1309-48-4
PUB Number 14792
Drugbank ID DB01377
Solubility practically insoluble in water

Basics

Magnesium oxide is a salt consisting of the elements magneisum and oxygen. In medicine, the compound is commonly used as a laxative for symptomatic relief of acid indigestion and stomach upset, and in dietary supplements for cardiovascular and neuromuscular health.

Pharmacology

Pharmacodynamics

When taken orally, magnesium oxide acts as a so-called osmotic laxative. This draws fluid from the body into the intestine, increasing stool mass and stimulating nerves in the colon wall. This stimulates intestinal peristalsis and subsequently leads to emptying of the intestinal contents. Dietary magnesium supplements have also been shown to reduce platelet aggregation by inhibiting the influx of calcium, a critical component of platelet aggregation.

Markus Falkenstätter

Markus Falkenstätter
Author

Markus Falkenstätter ist Autor zu pharmazeutischen Themen in der Medizin-Redaktion von Medikamio. Er befindet sich im letzten Semester seines Pharmaziestudiums an der Universität Wien und liebt das wissenschaftliche Arbeiten im Bereich der Naturwissenschaften.

Mag. pharm Stefanie Lehenauer

Mag. pharm Stefanie Lehenauer
Lector

Stefanie Lehenauer ist seit 2020 freie Autorin bei Medikamio und studierte Pharmazie an der Universität Wien. Sie arbeitet als Apothekerin in Wien und ihre Leidenschaft sind pflanzliche Arzneimittel und deren Wirkung.

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