| ATC Code | N02AC03 |
| CAS number | 302-41-0 |
| PUB number | 9331 |
| Drugbank ID | DB12492 |
| Empirical formula | C27H34N4O |
| Molar mass (g·mol−1) | 430,59 |
| Physical state | solid |
| Melting point (°C) | 225–227 |
Piritramide is a synthetic opioid analgesic marketed in certain European countries, including: Austria, Belgium, Czech Republic, Germany and the Netherlands. It is available in free form, is approximately 0.75 times more potent than morphine and is administered parenterally (by injection) for the treatment of severe pain.
Piritramide is a synthetic opioid and a µ-receptor agonist. Thus, the analgesic effect is due to binding to µ-receptors in the CNS.
After intravenous administration, the onset of analgesia is only 1-2 minutes, possibly related to its large lipophilicity. The volume of distribution is 0.7-1 L/kg after a single dose, 4.7-6 L/kg after steady-state concentrations are reached, and up to 11.1 L/kg after prolonged administration.
Nausea, vomiting, respiratory depression, and constipation are the most common side effects that occur with the use of piritramide. However, these occur less frequently than with the use of morphine and other opioids.
Markus Falkenstätter, BSc
Mag. pharm. Stefanie Lehenauer
Browse our extensive database of medications from A-Z, including effects, side effects, and dosage.
All active ingredients with their effects, applications, and side effects, as well as the medications they are contained in.
Symptoms, causes, and treatments for common diseases and injuries.
The presented content does not replace the original package insert of the medication, especially regarding the dosage and effects of individual products. We cannot assume liability for the accuracy of the data, as the data has been partially converted automatically. Always consult a doctor for diagnoses and other health-related questions.
© medikamio