Rupatadine is an active substance from the group of H1-antihistamines(selective histamine H1 receptor antagonist) and an inhibitor (antagonist) of platelet-activating factor (PAF) used for the symptomatic treatment of hay fever (allergic rhinitis).
Indications and use
Rupatadine is a second-generation H1-antihistamine and chemically belongs to azines. It is used for symptomatic relief of the nasal and non-nasal symptoms of seasonal allergic rhinitis and perennial allergic rhinitis in patients 2 years of age and older. In addition, it is also used for the symptomatic relief of chronic spontaneous urticaria.
Usually, rupatadine is used in the form of tablets when used for adults and as a juice when used for children. Standard dosages are 10 mg in tablets and 1 mg/ml in oral solution.
Rupatadine is dispensed only against a doctor's prescription.
The initial synthesis, preclinical and clinical development of rupatadine was carried out by GRUPO J. URIACH, S.L, a Spanish pharmaceutical company. It was launched in Spain in 2003 under the brand name Rupafin.