Always take CellCept exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure. The usual way to take CellCept oral suspension is as follows:
The first dose will be given within 72 hours after the transplant operation. The recommended daily dose is 10 ml suspension (2 g of the active ingredient) taken as 2 separate doses. This means taking 5 ml suspension in the morning and then 5 ml suspension in the evening.
Children (aged 2 to 18 years):
The dose given will vary depending on the size of the child. Your doctor will decide the most appropriate dose based on body surface area (height and weight). The recommended dose is 600 mg/m ² taken twice a day.
The first dose will be given within 5 days following the transplant operation. The recommended daily dose is 15 ml suspension (3 g of the active ingredient) taken as 2 separate doses. This means taking 7.5 ml suspension in the morning then 7.5 ml suspension in the evening.
No data are available to recommend the use of CellCept in children who have received a heart transplant.
The first dose of oral CellCept will be given to you at least 4 days after the transplant operation and when you are able to swallow oral medications. The recommended daily dose is 15 ml suspension (3 g of the active ingredient) taken as 2 separate doses. This means taking 7.5 ml suspension in the morning then 7.5 ml suspension in the evening.
No data are available to recommend the use of CellCept in children who have received a liver transplant.
Method and route of administration
It is recommended that the pharmacist reconstitutes CellCept oral suspension for you prior to dispensing.
To reconstitute the suspension the pharmacist will proceed as follows:
Preparation of suspension
1. Tap the closed bottle several times to loosen the powder.
2. Measure 94 ml of purified water in a graduated cylinder.
3. Add approximately half of the total amount of purified water to the bottle and shake the closed bottle well for about 1 minute.
4. Add the remainder of water and shake the closed bottle well for about 1 minute.
5. Remove child-resistant cap and push bottle adapter into neck of bottle.
6. Close bottle with child-resistant cap tightly. This will assure the proper seating of the bottle adapter in the bottle and child-resistant status of the cap.
7. Write the date of expiration of the reconstituted suspension on the bottle label. (The shelf-life of the reconstituted suspension is 2 months.)
Avoid inhalation or direct contact with skin or mucous membranes of the dry powder as well as direct contact of the reconstituted suspension with the skin. If such contact occurs, wash thoroughly with soap and water; rinse eyes with plain water.
To withdraw the suspension with the oral dispenser proceed as follows:
1. Shake closed bottle well for about 5 seconds before each use.
2. Remove child-resistant cap.
3. Before inserting the tip of the dispenser into bottle adapter, push the plunger completely down toward the tip of the dispenser. Insert tip firmly into opening of the bottle adapter.
4. Turn the entire unit (bottle and dispenser) upside down.
5. Pull the plunger out slowly until the desired amount of medication is withdrawn into the dispenser (see figure).
6. Turn the entire unit right side up and remove the dispenser slowly from the bottle.
7. Dispense directly into mouth and swallow. Do not mix with any liquid prior to dispensing.
8. Close bottle with child-resistant cap after each use.
9. Immediately after administration: Disassemble dispenser, rinse under running tap water and air dry prior to next use.
Care should be taken to avoid contact of the skin with the suspension. If such contact occurs, wash thoroughly with soap and water.
Treatment will continue for as long as you need immunosuppression to prevent you rejecting your transplanted organ.
If you take more CellCept than you should:
If you take more suspension than you have been told to take, or if someone else accidentally takes your medicine, immediately see a doctor or go to a hospital straight away.
If you forget to take CellCept:
If you forget to take your medicine at any time, take it as soon as you remember, then continue to take it at the usual times.
If you stop taking CellCept:
Stopping your treatment with CellCept may increase the chance of rejection of your transplanted organ. Do not stop taking your medicine unless your doctor tells you to.
If you have any further questions on the use of this product, ask your doctor.