Do not use INOmax
- If you (as the patient) or your child (as the patient) are allergic (hypersensitive) to nitric oxide or any other ingredients of INOmax. (see section 6 ?further information? where the full list of ingredients is provided).
- If you have been told that you (as the patient) or your child (as the patient) have an abnormal circulation within the heart.
Take special care with INOmax
Inhaled nitric oxide may not always be effective and thus other therapies may be considered necessary for you or your child.
Inhaled nitric oxide may influence the oxygen carrying capacity of the blood. This will be monitored by blood samples and if required the dose of inhaled nitric oxide must be reduced.
Nitric oxide may react with oxygen forming nitrogen dioxide that may cause airway irritation. Your or your child?s doctor will undertake monitoring of nitrogen dioxide and in case of elevated values the INOmax therapy will be adjusted, decreased accordingly.
Inhaled nitric oxide may have a mild but influence on the platelets (components that help the blood to clot) of you or your child and any signs of bleeding and or haematoma should be observed. If you see any signs or symptoms that may be associated to bleeding you should directly inform the doctor.
No effect of inhaled nitric has been documented in newborn babies with a malformation where the diaphragm is not fully complete, so called ?congenital diaphragmatic hernia?.
In newborn babies with special malformations of the heart, ?what doctors calls congenital heart defects? inhaled nitric oxide may cause a worsening of the circulation.
INOmax should not be used in preterm baby < 34 weeks of gestational age.
Using other medicines
The doctor will decide when to treat you or your child with INOmax and with other medicines, and will carefully supervise the treatment.
Please tell your doctor if you (as the patient) or your child (as the patient) are taking or have recently taken or used any other medicines, including medicines obtained without a prescription.
Some medicines can affect the ability of blood to carry oxygen. These include prilocaine (a local anaestheticused for pain relief in association to minor painful procedures e.g. suturing, and minor surgical or diagnostic procedures) or glyceryl trinitrate (used to treat chest pain). Your doctor will take care to check that the blood can carry enough oxygen when you are taking these medicines.
Pregnancy and breastfeeding
INOmax is not recommended for use during pregnancy and breastfeeding.
Tell your doctor before treatment with INOmax if you are pregnant, think you could be pregnant or are breastfeeding
Ask your doctor or pharmacist for advice before taking any medicine.