What Kineret contains
The active substance is anakinra. Each vial contains 100 mg of anakinra.
The other ingredients are:
sodium citrate, sodium chloride, disodium edetate, polysorbate 80 and sodium hydroxide and water for injections.
What Kineret looks like and contents of the pack
Kineret is a clear, colourless-to-white solution for injection in a vial. It may contain some translucent-to-white particles of protein. The presence of these particles does not affect the quality of the product.
Pack size of 1 vial.
Biovitrum AB (publ)
SE-112 76 Stockholm
Marketing Authorisation Holder:
Biovitrum AB (publ)
SE-112 76 Stockholm
This leaflet was last approved in
Information on how to give yourself an injection of Kineret
This section contains information on how to give yourself an injection of Kineret. It is important that you do not try to give yourself the injection unless you have received training from your doctor, nurse or pharmacist. If you have questions about how to inject, please ask your doctor, nurse or pharmacist for assistance.
How do you or the person injecting you, use the Kineret vial?
You will need to give yourself an injection at the same time every day. Kineret is injected just under the skin. This is called a subcutaneous injection.
To give yourself a subcutaneous injection you will need:
a new vial of Kineret
a sterile syringe and needles and
alcohol wipes or similar.
What should you do before you give yourself a subcutaneous injection of Kineret?
1. Take your Kineret vial out of the refrigerator.
2. Do not shake the vial.
3. Check the expiry date on the vial label (EXP). Do not use it if the date has passed the last day of the month shown.
4. Check the appearance of Kineret. It must be a clear, colourless-to-white solution. There may be some translucent-to-white particles of protein in the solution. The presence of these particles does not affect the quality of the product. The solution should not be used if it is discoloured or cloudy, or if any particles other than translucent-to-white particles are present.
5. For a more comfortable injection, leave at room temperature for approximately 30 minutes. Do not warm Kineret in any other way (for example, do not warm it in a microwave or in hot water).
6. Wash your hands thoroughly.
7. Find a comfortable, well-lit, clean surface and put all the equipment you need within reach.
How do you prepare your Kineret injection?
1. Remove the plastic top from the vial by pushing upwards to expose the rubber stopper.
2. Clean the stopper with a fresh alcohol wipe.
3. Remove the syringe and needles from their packaging. Attach the longer needle to the syringe and remove the cover. Do not touch the needle.
4. Pull the syringe plunger out, filling the syringe with air to the amount prescribed by your doctor.
5. Push the needle through the rubber stopper and introduce the air into the vial by pushing the plunger. Turn the vial upside down, pull on the plunger and fill the syringe with the correct amount of liquid. It is important that the needle is always in the liquid in order to prevent air bubbles forming in the syringe.
6. Remove the needle from the vial. Remove the needle from the syringe.
7. Put the short needle on the syringe and remove the cover. Do not touch the needle.
8. Hold the syringe with the needle pointing up to see if it has any air bubbles inside. If there are, gently press the plunger until all the air (but none of the liquid) has been removed.
The syringe is ready for you to use.
Where should you give your injection?
The most suitable places to inject yourself are the top of your thighs and the abdomen, except for the area around the navel. 41
Change the place that you inject each time so you don?t become sore in one area. If someone else is injecting for you, they can also use the back of your arms.
How do you give your injection?
1. Disinfect your skin by using the alcohol wipe and pinch the skin between your thumb and forefinger, without squeezing it.
2. Put the needle fully into the skin as shown by your nurse or doctor.
3. Pull slightly on the plunger to check that a blood vessel has not been punctured. If you see blood in the syringe, remove the needle and re-insert it in another place.
4. Inject the liquid slowly and evenly, always keeping your skin pinched.
5. After injecting the liquid, remove the needle and let go of your skin.
6. Only use each syringe for one injection. You must not use any Kineret that is left in the vial.
If you have any problems, please do not be afraid to ask your doctor or nurse for help and advice.
Disposing of used needles, syringes and vials
Do not put the cover back on used needles.
Keep used needles and syringes out of reach and sight of children
Never put the syringes and vials that you have used into your normal household rubbish bin.
The used syringes and vials should be disposed of in accordance with local requirements. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.