Always take LYRICA exactly as your doctor has instructed you. You should check with your doctor or pharmacist if you are not sure.
Your doctor will determine what dose is appropriate for you.
Peripheral and central neuropathic pain, epilepsy or Generalised Anxiety Disorder:
- Take the solution as instructed by your doctor.
- The dose, which has been adjusted for you and your condition, will generally be between 150 mg (7.5 ml) and 600 mg (30 ml) each day.
- Your doctor will tell you to take LYRICA either twice or three times a day. For twice a day take LYRICA once in the morning and once in the evening, at about the same time each day. For three times a day take LYRICA once in the morning, once in the afternoon and once in the evening, at about the same time each day.
If you have the impression that the effect of LYRICA is too strong or too weak, talk to your doctor or pharmacist.
If you are an elderly patient (over 65 years of age), you should take LYRICA normally except if you have problems with your kidneys.
Your doctor may prescribe a different dosing schedule and/or dose if you have problems with your kidneys.
Continue taking LYRICA until your doctor tells you to stop.
Administration:Instructions for use
LYRICA is for oral use only.
1. Open the bottle: Press downward on the cap and turn it counter-clockwise (Figure 1).
2. First time use only: A Press-In Bottle Adapter (PIBA) is provided with the oral syringe. This is the device that gets inserted into the neck of the bottle to make it easier to withdraw the solution using the oral syringe. If the PIBA is not already in place, remove the PIBA and 5 ml oral syringe from the plastic overwrap. With the bottle on a flat surface, insert the PIBA into the bottle neck while keeping the PIBA?s flat surface facing up and pressing on it (Figure 2).
3. Push the syringe plunger to the bottom of the barrel of the syringe (toward its tip) to remove excess air. Attach the syringe to the PIBA with a slight twisting motion (Figure 3).
4. Invert the bottle (with the syringe attached) and fill the syringe with the liquid by pulling the syringe plunger down to just beyond the graduation mark corresponding to the quantity in millilitres (ml) prescribed by your doctor (Figure 4). Remove air bubbles from the syringe by pushing the plunger up to the appropriate graduation mark.
5. Return the bottle to an upright position with the syringe still in the PIBA/bottle (Figure 5).
6. Remove the syringe from the bottle/PIBA (Figure 6).
7. Empty the contents of the syringe directly into mouth by pushing the syringe plunger to the bottom of the syringe barrel (Figure 7).
Note: Steps 4-7 may need to be repeated up to three times to obtain the total dose (Table 1).
[For example, a 150 mg (7.5 ml) dose will require two withdrawals from the bottle to achieve the entire dose. Using the oral syringe, first withdraw 5 ml and empty contents of syringe directly into the mouth, then refill the oral syringe with 2.5 ml and empty the remaining contents into the mouth.]
8. Rinse the syringe by drawing water into the syringe and pushing the syringe plunger to the bottom of the syringe barrel, at least three times (Figure 8).
9. Replace the cap on the bottle (leaving the PIBA in place in the bottle neck) (Figure 9).
Figure 1 Figure 2 Figure 3
Figure 4 Figure 5 Figure 6
Figure 7 Figure 8 Figure 9
Table 1. Oral Syringe Withdrawals to Deliver Prescribed Dose of Lyrica
Lyrica Dose mg Total Solution Volume ml First Syringe Withdrawal ml Second Syringe Withdrawal ml Third Syringe Withdrawal ml 25 1.25 1.25 Not required Not required 50 2.5 2.5 Not required Not required 75 3.75 3.75 Not required Not required 100 5 5 Not required Not required 150 7.5 5 2.5 Not required 200 10 5 5 Not required 225 11.25 5 5 1.25 300 15 5 5 5
If you take more LYRICA than you should
Call your doctor or go to the nearest hospital emergency unit immediately. Take your box or bottle of LYRICA oral solution with you. You may feel sleepy, confused, agitated, or restless as a result of taking more LYRICA than you should.
If you forget to take LYRICA
It is important to take your LYRICA oral solution regularly at the same time each day. If you forget to take a dose, take it as soon as you remember unless it is time for your next dose. In that case, just carry on with the next dose as normal. Do not take a double dose to make up for a forgotten dose.
If you stop taking LYRICA
Do not stop taking LYRICA unless your doctor tells you to. If your treatment is stopped it should be done gradually over a minimum of 1 week.
After stopping long and short-term LYRICA treatment, you need to know that you may experience certain side effects. These include, trouble sleeping, headache, nausea, feeling anxious, diarrhoea, flu-like symptoms, convulsions, nervousness, depression, pain, sweating, and dizziness. It is not clear at this time whether these symptoms occur more commonly or severely if you have been taking pregabalin for a longer period of time.
If you have any further questions on the use of this product, ask your doctor or pharmacist.