Do not take Orfadin
- if you are allergic (hypersensitive) to nitisinone or any of the other ingredients of Orfadin (see section 6).
Take special care with Orfadin
- if you get red eyes or any other signs of effects on the eyes. Contact your doctor immediately for an eye examination. Eye problems could be a sign of inadequate dietary control.
During the treatment, blood samples will be drawn in order for your doctor to check whether the treatment is adequate and to make sure that there are no possible side effects causing blood disorders.
Your liver will be checked at regular intervals because the disease affects the liver.
Follow-up by your doctor should be performed every 6 months. If you experience any side effects, shorter intervals are recommended.
Taking other medicines
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
Taking Orfadin with food and drink
If you start Orfadin treatment by taking it with food, it is recommended that you carry on taking it with food throughout your course of treatment.
Pregnancy and Breast-feeding
The safety of Orfadin has not been studied in pregnant and breast-feeding women. Please contact your doctor if you plan to become pregnant. If you become pregnant you should contact your doctor immediately.
Do not breast-feed while taking this medicine..
Driving and using machines
No studies on the effect on the ability to drive and use machines have been performed. If you experience side effects affecting the vision you should consider your ability to drive or use machines.