What is it and how is it used?
The name of your medicine is Trevaclyn. It contains two different active substances:
- nicotinic acid, a lipid modifying medicine, and
- laropiprant, which reduces symptoms of flushing, a common side effect of nicotinic acid.
The medicine comes as a modified-release tablet. This means one or more active substances are released slowly over a period of time.
Trevaclyn is used in addition to diet
- to lower your ?bad? cholesterol level. It does this by lowering the levels of total cholesterol, LDL cholesterol, fatty substances called triglycerides and apo B (a part of LDL) in the blood;
- to raise levels of ?good? cholesterol (HDL cholesterol) and apo A-I (a part of HDL).
What should I know about cholesterol?
Cholesterol is one of several fats found in your blood. Your total cholesterol is made up mainly of ?bad? (LDL) and ?good? (HDL) cholesterol.
LDL cholesterol is often called ?bad? cholesterol because it can build up in the walls of your arteries and form plaque. Over time, this plaque build-up can lead to a clogging of your arteries. This clogging can slow or block blood flow to vital organs such as the heart and brain. When the blood flow is blocked, the result can be a heart attack or stroke.
HDL cholesterol is often called ?good? cholesterol because it helps keep the ?bad? cholesterol from building up in the arteries and because it protects against heart disease.
Triglycerides are another fat in your blood. They may raise your risk of having heart problems.
In most people, at first there are no signs of cholesterol problems. Your doctor can measure your cholesterol with a simple blood test. Visit your doctor regularly to keep track of your cholesterol and discuss your goals with your doctor.
Trevaclyn is used if you need to improve cholesterol and fat levels in your blood (primary hypercholesterolaemia (heterozygous familial and non-familial) or mixed dyslipidaemia):
- when you cannot control your cholesterol levels with a statin (class of cholesterol-lowering medicines working in the liver);
- when you cannot tolerate a statin or when a statin is not recommended for you.
Trevaclyn can be used by itself or with other medicines to treat cholesterol problems. You should stay on a diet designed to lower cholesterol or other non-pharmacological treatments (e.g. exercise, weight reduction) while you take this medicine.