Saw palmetto (Serenoa repens)

Basics

Extract from the fruits of saw palmetto is used as an active ingredient in herbal medicines. It cancels the effects of male sex hormones (antiandrogen), has growth inhibitory (antiproliferative) and anti-inflammatory (anti-inflammatory) effects. It is used to relieve the symptoms of prostate enlargement. These symptoms include urination at night and decreased urine flow.

Dried Saw Palmetto Fruits (Fructus Sabal Serrulata) Getrocknete saw palmetto (Barna Tanko / iStock)

Saw palmetto fruits contain fatty acids, such as oleic acid, lauric acid or myristic acid, and phytosterols, such as stigmasterol or campesterol. Phytosterols are fatty plant compounds that are ingested with food. Saw palmetto (Serenoa repens or Sabal serrulata) is a member of the palm family, grows between 2 and 3 meters tall, and is found in the southeastern United States, particularly in Florida.

Saw palmetto fruits are popularly used in alternative medicine. Their effect could not be proven. The dried and ripe fruits are used as medicines. With the help of ethanol or other solvents, the ingredients are dissolved out (extracted) and used as extracts. The ingredients are thus in the solvent.

Effect

Saw palmetto fruit extract prevents the conversion of testosterone to dihydrotestosterone. Thus, the binding to the androgen receptors is reduced. It is important to note that saw palmetto fruit only improves symptoms, not treats the cause of prostate enlargement. Saw palmetto fruit also has an anti-inflammatory (anti-inflammatory) effect.

Dosage

Always take Saw Palmetto exactly as described in the package leaflet or exactly as agreed with your doctor.

The recommended intake is 320 mg per day. Saw palmetto fruit should be taken after meals, otherwise there is a possibility of gastrointestinal problems. The duration of taking saw palmetto fruit is prescribed by the attending physician.

Side effects

The following side effects may occur:

If you experience any of the following symptoms, stop taking saw palmetto fruit immediately:

Interactions

When taking the following medicines at the same time, interactions may occur:

  • with medicines that affect blood clotting (e.g., clopidogrel, acetylsalicylic acid), the effect may be increased
  • drugs from the group of non-steroidal anti-inflammatory drugs (NSAIDs) may increase the risk of bleeding in the gastrointestinal tract
  • hormone treatments with testosterone or other androgens, their effect may be decreased
  • antiandrogens may be increased by the effect of saw palmetto fruit
  • ingestion with metronidazole may cause nausea and vomiting
  • saw palmetto fruit may weaken the effect of birth control pills

Saw palmetto fruit should not be combined with the following foods and supplements:

Contraindications

Saw palmetto fruit must not be taken in the following cases:

  • in case of blood coagulation disorders (e.g. hemophilia)
  • in liver diseases
  • pancreatic disorders
  • in case of known allergy to saw palmetto fruit or its ingredients

Age restriction

Saw palmetto fruit is not intended for children and adolescents under 18 years of age.

Pregnancy & Lactation

Since saw palmetto fruit is used to treat the symptoms of prostate enlargement in men, it is not intended for use during pregnancy and breastfeeding. Therefore, its use should be refrained from.

Thomas Hofko

Thomas Hofko

Mag. pharm. Stefanie Lehenauer

Mag. pharm. Stefanie Lehenauer



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The presented content does not replace the original package insert of the medication, especially regarding the dosage and effects of individual products. We cannot assume liability for the accuracy of the data, as the data has been partially converted automatically. Always consult a doctor for diagnoses and other health-related questions.

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