Basics
Titanium dioxide is mainly used as an excipient in the pharmaceutical industry. Excipients are substances that give the finished medication special properties or are only used as a harmless filler. Titanium dioxide is used as a white pigment in tablets and capsules. However, titanium dioxide is also used in sunscreens, as it acts as a mineral UV filter to protect UVA and UVB rays from penetrating the skin.
Titanium dioxide should not be inhaled as it is carcinogenic and can cause inflammation. In 2021, the European Food Safety Authority (EFSA) came to the conclusion that titanium dioxide can no longer be used as a food additive. However, it is still permitted in medicines, but is usually already replaced or omitted. Patients with chronic inflammatory bowel disease should avoid titanium dioxide altogether, as this can lead to an increase in inflammation and there is also a risk of titanium dioxide accumulating in the spleen.