Sciatic nerve irritation (sciatica)

Dull, throbbing pain
Numbness
pulling or tearing pains
Micturition disorders
Paralysis
Nerve injury
Abscess in the area of the spine
Pressure damage (such as herniated disc)
Lack of exercise
Incorrect posture
Nerve inflammation
Increasing age
Spondylolisthesis
Herniated disc
Skeletal disorders
Tumours in the area of the nerve root
Medication
surgical procedure
Physiotherapy
Sports
physical sparing

Basics

Sciatica is the term used to describe pain and discomfort caused by irritation of the sciatic nerve. Usually the complaints are described as acute dull, pressing or pulling pains in the back area, which extend from the back of the thigh into the leg and seem to come from the sacrum. A distinction must be made here between lumbago (lumbago), in which the pain is expressed exclusively in the back region.

Graphic representation of the sciatic plexus Ischiasplexus (Servier Medical Art by Servier / Creative Commons Attribution 3.0 unported license)

The sciatic nerve, also known as the sciatic nerve, is the strongest and thickest nerve in the body and transmits stimuli and sensations from the legs via the spinal cord to the brain. The structure of the sciatic nerve is similar to that of a peripheral nerve. This is analogously composed of several nerve roots, which together form the so-called plexus (braid). At the level of the knee, the sciatic nerve divides into the tibial nerve and the peroneal nerve. Sciatica now occurs when the sciatic nerve or other nerve fibers in its course become irritated or pinched at a certain point, for example due to pressure or inflammation. This results in pain that radiates down only one leg.

Causes

The causes of sciatic nerve irritation can be of various nature, but are mainly due to various diseases, as well as mechanical pressure of the nerves and/or inflammation.

In most cases, the origin can be found directly in the nerve roots in the spinal cord. The sciatic nerve can be particularly irritated by the following factors:

Lack of exercise

Too little exercise can imbalance the back, causing muscles to tense quickly and tendon insertions to become severely irritated.

Incorrect posture

Sitting in a slouched position for long periods of time, the wrong posture can lead to shortened muscle fibers, which can subsequently irritate the nerves severely.

Pressure damage


  • Herniated disc:

    A herniated disc in the lumbar spine is one of the most common causes of pressure damage-related sciatic nerve irritation. The function of the intervertebral discs can best be compared to that of a shock absorber. Inside, they contain a gel-like substance (gelatinous core) surrounded by a taut ligament (fibrous ring). The intervertebral discs are located between the individual vertebral bodies and serve to protect the spinal column. With advancing age or through intensive stress, the fibrous rings take damage and can tear. As a result, bile escapes and presses on the nerve roots located in the spinal canal.
  • Metastases, tumors, hemorrhages, inflammatory swellings:

    These can lead to partial destruction of the vertebrae or press on the nerves from the outside.
  • Entrapment of nerves:

    Pain may also be due to pinching or squeezing of the nerves by the bony portions of the spine.

Nerve inflammation

  • Lyme disease:

    Painful inflammation of the nerve root can be caused by the tick-borne bacterial infectious disease Lyme disease.
  • Shingles:

    Another trigger of nerve inflammation can be the herpes zoster viruses that cause the clinical picture of shingles. If there is a defense weakness, these viruses migrate along the nerves, while the predominantly survive in the nerve roots. In this case, the sciatic nerve can also be affected, resulting in great pain. Another symptom is itchy blisters below the knee.

Neuroforamstenosis

Through holes in the intervertebral discs (i.e., intervertebral discs), also called neuroforamina, the spinal cord nerves exit the spinal canal of the spinal column at the respective vertebra to both sides. If these holes are narrowed, this is called neuroforaminal stenosis or neuroforaminal narrowing. This narrowing can then irritate and damage the nerves. If the canals are narrowed directly in the spine, this is called spinal stenosis or spinal canal stenosis. This can also become the cause of sciatica if the spinal cord nerves become too irritated or damaged in the process.

Osteoporosis

Changes in the bones caused by osteoporosis (i.e. bone loss) can lead to vertebral fractures in accidents. Consequently, the nerves may also be damaged in the process, which could lead to sciatica.

Diabetes and obesity

Diabetes mellitus and obesity (i.e., pathological overweight) can further promote sciatica.

Abscess

An abscess located in the spine may also be a cause of sciatic nerve irritation.

Injections

The result of an intramuscular injection may be an abscess in the connective tissue or gluteal muscles that presses on that part of the nerve that goes toward the buttocks and thighs.

Surgery

Invasive surgery, such as hip replacement surgery, may be another cause of sciatic nerve irritation.

Childbirth

Pain in this area can also occur during childbirth. This is explained by the fact that the baby's head is close to the course of the nerve in the pelvis.


The sciatic nerve irritation can cause different types of complaints, but most of them depend on the location of the nerve irritation, but less on the underlying disease that causes the sciatica.

Another form of sciatic nerve irritation is the irritation of several nerve roots in the area of the spine. Here, the pain in the leg is limited to a strip-shaped area, which is also called radicular pain in medical jargon (Lat.: Radix= root). Mainly this pain runs on the back of the upper and lower leg, as well as on the sole and outside of the foot.

However, pseudoradicular pain often occurs as well. This is the term used to describe pain that cannot be precisely localized. Here, the cause lies in the small vertebral arch joints. These can either have a malposition or show signs of wear (facet syndrome). However, another cause can also be due to a malposition of the pelvic-cruciate joint (sacroiliac joint) or due to tension in the surrounding muscles.

Symptoms

Generally, symptoms of sciatica are related to the type and severity of nerve injury. A sudden onset of pain after movement is often reported.

In mild nerve injury:

  • Dull, throbbing pain
  • Pain spreads from the lower back to the foot
  • Pain often only on one side of the body
  • Limited movement when standing up
  • Complaints are felt most strongly in the morning and after longer periods of rest
  • Sneezing, coughing, lying, sitting or standing increase the feeling of pain
  • Walking reduces the feeling of pain

With moderate nerve injury:

  • Itching or tingling in the area of the buttocks and the legs
  • Feeling of weakness in the affected leg area
  • Numbness in the affected leg

In case of severe nerve injury:

  • Severe disturbances during urination or defecation with numbness

In case of ischialgia caused by a herniated disc

  • Pain that may cause a pulling or tearing sensation
  • A pain that is aggravated by coughing, sneezing or pressing and radiates down the leg
  • A sensory disturbance occurring in partial portions of the leg, such as numbness or "formication"
  • Impairment of some muscle groups due to paralysis - for example, the inability of some patients to stand on their toes

In severe cases:

  • Micturition disorders (i.e., disturbance of bladder emptying) or difficulty emptying the rectum.

It should be noted, however, that not every herniated disc is accompanied by sciatic nerve irritation and associated pain. A computed tomography (CT) scan can detect herniated discs in the elderly that are asymptomatic and unnoticed.

For sciatica due to Lyme disease.

  • Severe, shooting pain at night
  • Paralysis of single or multiple muscle groups of the legs

Rarely:

  • Sensory disturbances and associated numbness, as well as burning sensations of discomfort
Physiotherapuet touches back of woman Körperliche Untersuchung bei der Anamnese (Yan Krukau / Pexels)

Diagnosis

1. anamnesis

Before a neurological examination is performed, the patient's medical history should first be taken. In this way, a sciatic nerve irritation caused by a herniated disc, for example, can be well diagnosed. Particular emphasis should be placed on body malposition, loss of sensation and signs of paralysis.

2. imaging procedures

X-rays of the spine are taken to obtain a more accurate picture.

To diagnose a herniated disc as the cause, a computed tomography or magnetic resonance imaging is usually performed. In some cases, this can even reveal the location where the herniated disc is pressing on the nerve root. To be on the safe side, a contrast medium image of the spinal canal and the nerve root canals (myelogram or myelo-CT or myelo-MR) can be made.

A rather unusual method today is discography. Here, the contrast medium is administered directly into the area of the intervertebral discs.

3. neurological examinations

An electromyogram (EMG) can be used to determine the location of nerve damage. It can also be used to estimate the duration and extent of nerve damage.

4. blood and nerve fluid diagnostics

If the treating physician suspects an inflammatory disease or an infection with herpes zoster or Borrelia as the cause, a blood test is usually performed. A spinal fluid (CSF) examination may also be necessary in this case.

Therapy

General measures

The first priority in the treatment of ischialgia is to relieve the current pain. Acute pain can be counteracted with relieving positioning, for example by a stepped bed. By elevating the legs, ideally at a 90-degree angle, the tensile load on the sciatic nerve can be reduced. It is important to remain in regular exercise despite the pain, as complete bed rest has been shown to prevent healing of the pain and is more likely to exacerbate and chronify the pain. Patients should be educated that physical activity is harmless to the course of the disease and should be maintained as much as possible.

Back massage Massagen lockern und durchbluten die Muskulatur (Toa Heftiba / Unsplash)

a) Non-medicinal measures

  • Physiotherapy: helps to correct painful incorrect postures and thus contributes primarily to relieving the pain, and later to strengthening the musculature
  • Massages, heat, red light: can loosen tense muscles and improve blood circulation in the back and trunk muscles.

b) Medicinal measures

Woman takes medicine Zur medikamnetösen Therapie werden zumeist Analgetika eingesetzt (JESHOOTS.com / Pexels)

If non-opioid analgesics are not sufficiently effective, opioids are also prescribed according to a graduated schedule. Intravenous, intramuscular or subcutaneous administration of the drugs do not show faster or better efficacy compared to oral administration of analgesics. Because of side effects and complications, this form of administration is not recommended for pain management. In order to prevent the nerve cells from forming a so-called "pain memory" as a result of habituation to the medication, pain therapy should be used primarily only for acute pain.

c) surgical measures

  • rarely, mostly in case of progressive paralysis or loss of sensibility
  • in case of a herniated disc with chronic pain

Treatment depending on cause

Herniated disc

  • several hours daily elevation of the legs (stepped bed) only in case of extreme pain
  • general rest, heat and medication as needed
  • Bed rest not absolutely necessary for moderate pain
  • physiotherapy to relieve pain and strengthen muscles
  • in case of paralysis, surgery should be performed

Lyme disease

Approx. 2-week oral or intravenous antibiotic therapy, e.g. with:

Shingles

Abscess

surgical removal with simultaneous use of antibiotics

Pressure relief

Pain usually heals on its own, no active treatment indicated

Forecast

In general, the prospects of recovery from sciatic nerve irritation are very good. Conservative therapy for herniated discs usually makes the pain disappear. In case of surgical intervention, the advantages and disadvantages of the operation should be discussed with the patient.

Spontaneous healing of sciatic nerve irritation caused by pressure loads or postoperative procedures is often very good, although it may take several months. Postpartum sciatic nerve irritation also usually heals within a few weeks.

Sciatic nerve irritation caused by borrelia can be treated very well with antibiotics. In this case, the pain can improve after only 5 days. However, many patients still complain about pain half a year later. More rarely, sciatic nerve irritation caused by shingles can occur. The chances of recovery are also very good in this case. If the patient's immune system is unfavorable, a long-lasting pain disorder can also occur. Increasing age is also a risk factor. Patients over the age of 70 often develop postzosteric neuralgia, which is characterized by sudden stabbing pain.

Illustration of the Lyme disease bacterium Borreliose-Bakterium (Medical Graphics / creative commons CC BY-ND 3.0)

An irritation of the sciatic nerve caused by Borrelia bacteria can be treated very well with antibiotics. In this case, the pain can improve after only 5 days. However, many patients still complain about pain half a year later. More rarely, sciatic nerve irritation caused by shingles can occur. The chances of recovery are also very good in this case. If the patient's immune system is unfavorable, a long-lasting pain disorder can also occur. Increasing age is also a risk factor. Patients over the age of 70 often develop postzosteric neuralgia, which is characterized by sudden stabbing pain.

Prevent

Strengthen back muscles

This can be done through muscle training and physiotherapy , which are offered in a back school, for example.

Ergonomic measures at the workplace

The workplace should be designed to be back-friendly by allowing upright sitting with correct distance to the computer, table and keyboard. Posture should also be corrected repeatedly while working.

Avoid excess weight

Excess weight puts a strain on the back, which is why weight reduction is advisable to prevent back pain.

Correct lifting of heavy loads

  • The load should never be lifted with arms outstretched. It should be squatted and the load lifted with bent arms.
  • Loads should also never be carried far from the body
  • It is advisable to distribute the weight evenly over the body to avoid loading the body only on one side.
  • If possible, carrying heavy loads should be generally avoided and should be done only in the most urgent cases.

Strengthening the immune system

The risk of suffering nerve root diseases caused by viruses such as Lyme disease or shingles can be reduced by strengthening the immune system. A balanced diet rich in fruits and vegetables, as well as a balanced mood and endurance sports in the fresh air contribute to this. Vaccination also protects against the chickenpox virus (herpes zoster virus), which causes shingles.

Olivia Malvani, BSc

Olivia Malvani, BSc

Dr. med. univ. Moritz Wieser

Dr. med. univ. Moritz Wieser



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