Imatinib Zentiva will only be prescribed to you by a doctor with experience in medicines to treat blood cancers.
Follow all your doctor’s instructions carefully, even if they differ from the general information contained in this leaflet.
Do not take Imatinib Zentiva:
- if you are allergic to imatinib or any of the other ingredients of this medicine listed in section 6. If this applies to you, tell your doctor without taking Imatinib Zentiva.
If you think you may be allergic but are not sure, ask your doctor for advice.
Warnings and precautions
Talk to your doctor before taking Imatinib Zentiva:
- if you have or have ever had a liver, kidney or heart problem.
- if you are taking the medicine levothyroxine because your thyroid has been removed. If any of these apply to you, tell your doctor before taking Imatinib Zentiva.
During treatment with Imatinib Zentiva, tell your doctor straight away if you put on weight very quickly. Imatinib Zentiva may cause your body to retain water (severe fluid retention).
While you are taking Imatinib Zentiva, your doctor will regularly check whether the medicine is working. You will also have blood tests and be weighed regularly.
Children and adolescents
Imatinib Zentiva is also a treatment for children with CML. There is no experience in children with CML below 2 years of age.
Some children and adolescents taking Imatinib Zentiva may have slower than normal growth. The doctor will monitor the growth at regular visits.
Other medicines and Imatinib Zentiva
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines, including medicines obtained without a prescription (such as paracetamol) and including herbal medicines
(such as St. John’s Wort). Some medicines can interfere with the effect of Imatinib Zentiva when taken together. They may increase or decrease the effect of Imatinib Zentiva, either leading to increased side effects or making Imatinib Zentiva less effective. Imatinib Zentiva may do the same to some other medicines.
Pregnancy, breast-feeding and fertility
- If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine.
- Imatinib Zentiva is not recommended during pregnancy unless clearly necessary as it may harm your baby. Your doctor will discuss with you the possible risks of taking Imatinib Zentiva during pregnancy.
- Women who might become pregnant are advised to use effective contraception during treatment.
- Do not breast-feed during the treatment with Imatinib Zentiva.
- Patients who are concerned about their fertility while taking Imatinib Zentiva are advised to consult with their doctor.
Driving and using machines
You may feel dizzy or drowsy or get blurred vision while taking this medicine. If this happens, do not drive or use any tools or machines until you are feeling well again.