Do not take Esomeprazol Actavis
- if you are allergic to esomeprazole or any of the other ingredients of this medicine (listed in Section 6).
- if you are allergic to other proton pump inhibitor medicines (e.g. pantoprazole, lanzoprazole, rabeprazole, omeprazole).
- if you are taking a medicine containing nelfinavir (used to treat HIV).
Do not take Esomeprazol Actavis if any of the above apply to you. If you are not sure, talk to your doctor or pharmacist before taking Esomeprazol Actavis.
Warnings and precautions
Talk to your doctor or pharmacist before taking Esomeprazol Actavis:
- if you have severe liver problems.
- if you have severe kidney problems.
Esomeprazol Actavis may hide the symptoms of other diseases. Therefore, if any of the following happen to you before you start taking Esomeprazol Actavis or while you are taking it, talk to your doctor straight away:
- you lose a lot of weight for no reason and have problems swallowing.
- you get stomach pain or indigestion.
- you begin to vomit food or blood.
- you pass black stools (blood-stained faeces).
If you have been prescribed Esomeprazol Actavis “on demand” you should contact your doctor if your symptoms continue or change in character.
Taking a proton pump inhibitor like Esomeprazol Actavis, especially over a period of more than one year, may slightly increase your risk of fracture in the hip, wrist or spine. Tell your doctor if you have osteoporosis or if you are taking corticosteroids (which can increase the risk of osteoporosis).
Other medicines and Esomeprazol Actavis
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. This is because Esomeprazol Actavis can affect the way some medicines work and some medicines can have an effect on Esomeprazol Actavis.
Do not take Esomeprazol Actavis if you are taking a medicine containing nelfinavir (used to treat HIV).
Tell your doctor or pharmacist if you are taking any of the following medicines:
- Atazanavir (used to treat HIV).
- Ketoconazole, itraconazole or voriconazole (used to treat infections caused by a fungus).
- Erlotinib (used to treat cancer).
- Citalopram, imipramine or clomipramine (used to treat depression).
- Diazepam (used to treat anxiety, relax muscles or in epilepsy).
- Phenytoin (used in epilepsy). If you are taking phenytoin, your doctor will need to monitor you when you start or stop taking Esomeprazol Actavis.
- Medicines that are used to thin your blood, such as warfarin. Your doctor may need to monitor you when you start or stop taking Esomeprazol Actavis.
- Cilostazol (used to treat intermittent claudication – a pain in your legs when you walk which is caused by an insufficient blood supply).
- Cisapride (used for indigestion and heartburn).
- Digoxin (used for heart problems).
- Methotrexate (a chemotherapy medicine used in high doses to treat cancer) – if you are taking a high dose of methotrexate, your doctor may temporarily stop your Esomeprazol Actavis treatment.
- Rifampicin (used for treatment of tuberculosis).
- St John’s wort (Hypericum perforatum) (used to treat depression).
If your doctor has prescribed the antibiotics amoxicillin and clarithromycin as well as Esomeprazol Actavis to treat ulcers caused by Helicobacter pylori infection, it is very important that you tell your doctor about any other medicines you are taking.
Esomeprazol Actavis with food and drink
You can take your tablets with food or on an empty stomach.
Pregnancy and breast-feeding
If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
Your doctor will decide whether you can take Esomeprazol Actavis during this time.
It is not known if Esomeprazol Actavis passes into breast milk. Therefore, you should not take Esomeprazol Actavis if you are
Driving and using machines
Esomeprazol Actavis is not likely to affect your ability to drive or use any tools or machines.
Esomeprazol Actavis contains sucrose
Esomeprazol Actavis gastro-resistant tablets contain sucrose, which is a type of sugar. If you have been told by your doctor that you have an intolerance to some sugars, talk to your doctor before taking this medicine.